Author

A. Rodriguez Gama

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:non-human primate· 1

Frequent Co-Authors

J. J. Lange· 3 shared R. Halfmann· 3 shared J. R. Unruh· 2 shared J. Wu· 2 shared M. Cook· 2 shared S. Venkatesan· 2 shared T. Miller· 2 shared A. Box· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersBiophysics

J. J. Lange

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Adaptor protein supersaturation drives innate immune signaling and cell fate

A. Rodriguez Gama, T. Miller, S. Venkatesan, J. J. Lange, J. Wu, X. Song, W. D. Bradford, M. Cook, J. R. Unruh, R. Halfmann

The paper identifies DFD adaptors as energy reservoirs through supersaturation, showing their role in innate immune signaling and cell fate decisions.

bioRxiv · Mar 20, 2023 · PreprintBiophysics

A nucleation barrier spring-loads the CBM signalosome for binary activation

A. Rodriguez Gama, T. Miller, J. J. Lange, J. Unruh, R. Halfmann

The paper investigates the CBM signalosome's binary activation mechanism, showing that BCL10's nucleation barrier stores energy for rapid NF-κB activation upon stimulation.

bioRxiv · Jan 28, 2022Cell Biology

Quantifying nucleation in vivo reveals the physical basis of prion-like phase behavior

T. Khan, T. Kandola, J. Wu, E. Ketter, S. Venkatesan, J. J. Lange, A. Rodriguez Gama, A. Box, J. R. Unruh, M. Cook, R. Halfmann

The paper quantifies nucleation in living cells using DAmFRET and shows that kinetic barriers influence prion-like phase behavior and protein aggregation.

bioRxiv · Apr 19, 2018Biophysics