Author

A. Rodriguez-Meira

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. J. Mead· 3 shared A. Hamblin· 2 shared B. Psaila· 2 shared C. Harrison· 2 shared E. Papaemmanuil· 2 shared I. Antony-Debre· 2 shared M. Bashton· 2 shared M. Drummond· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

A. J. Mead

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Author profile →

3 papers

Recent·Most cited

Chromothripsis orchestrates leukemic transformation in blast phase MPN through targetable amplification of DYRK1A

C. K. Brierley, B. H. Yip, G. Orlando, H. Goyal, S. Wen, J. Wen, M. F. Levine, M. G. Jakobsdottir, A. Rodriguez-Meira, A. Adamo, M. Bashton, A. Hamblin, S. A. Clark, J. O'Sullivan, L. Murphi, , A. J. Mead

The paper identifies chromothripsis-induced amplification of DYRK1A in blast phase MPN as a driver of aggressive disease and a potential therapeutic target.

bioRxiv · Dec 8, 2023 · PreprintCancer Biology

Deciphering TP53 mutant Cancer Evolution with Single-Cell Multi-Omics

A. Rodriguez-Meira, R. Norfo, W. X. Wen, A. L. Chedeville, H. Rahman, J. OSullivan, G. Wang, E. Louka, W. Kretzschmar, A. Paterson, C. Brierley, J.-E. Martin, C. Demeule, M. Bashton, N. Sousos, , A. J. Mead

The paper uses single-cell multi-omic analysis to study TP53-mutant cancer evolution in leukaemia, identifying a role for chronic inflammation in promoting TP53 mutant clones.

bioRxiv · Mar 28, 2022 · PreprintCancer Biology

Single cell genotyping of matched bone marrow and peripheral blood cells in treatment naive and AZA-treated MDS and CMML

A. Schnegg-Kaufmann, J. A. I. Thoms, G. S. Bhuyan, H. R. Hampton, L. Vaughan, K. Rutherford, P. M. Kakadia, E. M. V. Johansson, T. Failes, G. M. Arndt, J. Koval, R. Lindeman, P. Warbuton, A. Rodriguez-Meira, A. J. Mead, , J. E. Pimanda

This study examines the contribution of mutated hematopoietic stem and progenitor cells to blood cell populations in MDS and CMML before and after AZA treatment.

bioRxiv · Jan 20, 2022 · PreprintCancer Biology