Author

R. L. Tiwari

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:metabolomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Chareunsouk· 2 shared J. T. Rodgers· 2 shared M. Ederer· 2 shared M. H. Raval· 2 shared S. Ahsan· 2 shared A. B. Hwang· 1 shared A. S. Brack· 1 shared D. Pormislow· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

A. Chareunsouk

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Wnt5a-Cdc42 axis controls aging and rejuvenation of hair-follicle stem cells

R. L. Tiwari, P. Mishra, N. Martin, N. O. George, V. Sakk, K. Soller, K. Nalapareddy, K. Nattamai, K. S. Kochanek, M. C. Florian, H. Geiger

This study identifies a Wnt5a-Cdc42 signaling axis that regulates hair-follicle stem cell aging and rejuvenation, showing that inhibiting Cdc42 activity restores canonical Wnt signaling and promotes hair regeneration.

bioRxiv · Oct 22, 2020Cell Biology

Metabolism of glucose and glutamine is critical for skeletal muscle stem cell activation.

J. T. Rodgers, S. Ahsan, M. H. Raval, M. Ederer, R. L. Tiwari, A. Chareunsouk

This study identifies glucose and glutamine as critical substrates for skeletal muscle stem cell activation, showing they provide metabolic intermediates necessary for cell cycle entry beyond ATP production.

bioRxiv · Jul 28, 2020 · PreprintCell Biology

PDH Mediated Mitochondrial Respiration Controls the Speed of Muscle Stem Cell Activation in Muscle Repair and Aging

M. H. Raval, P.-C. Cheng, N. Guardino, S. Ahsan, H. Zhou, R. L. Tiwari, L. Wang, A. Chareunsouk, M. Ederer, A. B. Hwang, M. Ellenberger, R. Pepin, D. Pormislow, K. Shen, A. S. Brack, J. T. Rodgers

This study shows that mitochondrial respiration via PDH controls the speed of muscle stem cell activation, which declines with age, and that restoring PDH activity can improve muscle regeneration in aged mice.

bioRxiv · Feb 14, 2020 · PreprintCell Biology