Author

A. S. Khatpe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. M. Storniolo· 2 shared D. Chen· 2 shared H. Gao· 2 shared H. Nakshatri· 2 shared P. Bhat-Nakshatri· 2 shared P. C. McGuire· 2 shared Y. Liu· 2 shared C. Erdogan· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCancer Biology

A. M. Storniolo

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2 papers

Recent·Most cited

Single nuclei chromatin accessibility and transcriptomic map of breast tissues of women of diverse genetic ancestry

P. Bhat-Nakshatri, H. Gao, A. S. Khatpe, P. C. McGuire, C. Erdogan, D. Chen, G. Jiang, F. New, R. German, A. M. Storniolo, Y. Liu, H. Nakshatri

The paper develops a chromatin accessibility and gene expression atlas of human breast tissues from 92 donors of diverse genetic ancestry, identifying 10 cell types and ancestry-dependent gene expression patterns.

bioRxiv · Oct 4, 2023 · PreprintCancer Biology

BRCA1 and BRCA2 germline mutations driven signaling pathway alterations are sufficient to initiate breast tumorigenesis by the PIK3CAH1047R oncogene.

P. Bhat-Nakshatri, A. S. Khatpe, D. Chen, K. Batic, H. Mang, C. Herodotou, P. C. McGuire, X. Xuei, H. Gao, Y. Liu, G. Sandusky, A. M. Storniolo, H. Nakshatri

This paper compares single-cell transcriptomes of BRCA1/2 mutation carriers and non-carriers to show how these mutations alter signaling pathways and drive breast cancer development through PIK3CA mutations.

bioRxiv · Jul 26, 2023 · PreprintCancer Biology