Author

H. Mang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Organism:plant (other)· 4 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

D. Choi· 3 shared H. Kim· 3 shared H.-Y. Lee· 3 shared Y.-E. Seo· 3 shared C. Segonzac· 2 shared M.-S. Kim· 2 shared S. Oh· 2 shared A. M. Storniolo· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersPlant Biology

D. Choi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

BRCA1 and BRCA2 germline mutations driven signaling pathway alterations are sufficient to initiate breast tumorigenesis by the PIK3CAH1047R oncogene.

P. Bhat-Nakshatri, A. S. Khatpe, D. Chen, K. Batic, H. Mang, C. Herodotou, P. C. McGuire, X. Xuei, H. Gao, Y. Liu, G. Sandusky, A. M. Storniolo, H. Nakshatri

This paper compares single-cell transcriptomes of BRCA1/2 mutation carriers and non-carriers to show how these mutations alter signaling pathways and drive breast cancer development through PIK3CA mutations.

bioRxiv · Jul 26, 2023 · PreprintCancer Biology

Ptr1 and ZAR1 immune receptors confer overlapping and distinct bacterial pathogen effector specificities

Y. J. Ahn, H. Kim, S. Choi, C. Mazo-Molina, M. Prokchorchik, N. Zhang, B. Kim, H. Mang, H. Yoon, C. Segonzac, G. Martin, A. Schultink, K. H. Sohn

The paper identifies effector recognition specificities of NbPtr1 and NbZAR1 in N. benthamiana and shows their distinct and overlapping roles in detecting bacterial effectors.

bioRxiv · May 16, 2022Plant Biology

The Phytophthora capsici RxLR effector CRISIS2 has roles in suppression of PTI and triggering cell death in host plant

H. Mang, Y.-E. Seo, H.-Y. Lee, H. Kim, H. Jeon, X. Yan, S. Lee, S. A. Park, M.-S. Kim, C. Segonzac, D. Choi

This study identifies CRISIS2, an RxLR effector from Phytophthora capsici, which suppresses plant immunity by interacting with PMA and BAK1, leading to cell death and enhanced pathogen virulence.

bioRxiv · Mar 21, 2022Plant Biology

Plant NLR targets P-type ATPase for executing plasma membrane depolarization leading to calcium influx and cell death

D. Choi, H.-Y. Lee, Y.-E. Seo, J. H. Lee, S. E. Lee, S. Oh, J. Kim, S. Jung, H. Kim, H. Park, S. Kim, H. Mang

The paper shows that the plant NLR CCA309 targets P-type ATPase to cause membrane depolarization, calcium influx, and cell death during hypersensitive response.

bioRxiv · Aug 30, 2020 · PreprintPlant Biology

Genome-wide functional analysis of hot pepper immune receptors reveals an autonomous NLR cluster in seed plants

H.-Y. Lee, H. Mang, Y.-E. Seo, M.-S. Kim, S. Oh, S.-B. Kim, D. Choi

This study identifies an autonomous NLR cluster in seed plants through functional analysis of hot pepper immune receptors, revealing conserved autoactive NLRs that trigger cell death independently of helper NLRs.

bioRxiv · Dec 16, 2019 · PreprintPlant Biology