Author

A. S. Nam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:scRNA-seq· 3 Approach:deep learning· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

R. Chaligne· 3 shared D. A. Landau· 2 shared F. Izzo· 2 shared G. Abu-Zeinah· 2 shared N. D. Omans· 2 shared O. Abdel-Wahab· 2 shared P. Smibert· 2 shared R. Hoffman· 2 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersCancer Biology

R. Chaligne

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Type 1 interferon perturbates clonal competition by reshaping human blood development

C. Lama, D. Isakov, S. Rosenberg, M. Quijada-Alamo, M. S. Saurty-Seerunghen, S. Moein, T.-A. Abera, O. Sakaguchi, M. Totwani, G. Freed, C.-L. Poon, N. Parghi, A. Kubas-Meyer, A. X. Xie, M. Omar, , A. S. Nam

The paper investigates how type 1 interferon affects clonal competition in human blood development by altering HSC differentiation states and clonal fitness.

bioRxiv · Sep 28, 2022Cancer Biology

Using the Dynamic Forward Scattering Signal for Optical Coherence Tomography based Blood Flow Quantification

A. S. Nam, B. J. Vakoc, B. Braaf

This paper explores using forward-scattered light in optical coherence tomography to quantify blood flow, showing it is orientation-insensitive for vessels orthogonal to the imaging beam and demonstrating its use in human retinal and choroidal vessels.

bioRxiv · Feb 1, 2022Bioengineering

Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation

A. S. Nam, N. Dusaj, F. Izzo, R. Murali, R. M. Myers, T. Mouhieddine, J. Sotelo, S. Benbarche, M. Waarts, F. Gaiti, S. Tahri, R. Levine, O. Abdel-Wahab, L. A. Godley, R. Chaligne, , D. Landau

This study uses single-cell multi-omics to show DNMT3A R882 mutations cause hypomethylation and alter progenitor cell fates in clonal hematopoiesis.

bioRxiv · Jan 14, 2022 · PreprintCancer Biology

High throughput droplet single-cell Genotyping of Transcriptomes (GoT) reveals the cell identity dependency of the impact of somatic mutations

A. S. Nam, K.-T. Kim, R. Chaligne, F. Izzo, C. Ang, G. Abu-Zeinah, N. D. Omans, A. Pastore, J. Taylor, A. Alonso, M. Mariani, J. R. Cubillos-Ruiz, W. Tam, R. Hoffman, J. M. Scandura, , D. A. Landau

This study introduces GoT, a high-throughput method linking single-cell genotypes and transcriptomes, revealing that somatic mutations' transcriptional effects depend on cell identity.

bioRxiv · Oct 16, 2018Cancer Biology