A. Santiago

Aggregated gene co-expression networks for predicting transcription factor regulatory landscapes in a non-model plant species

The paper evaluates co-expression network aggregation methods in grapevine to predict transcription factor regulatory landscapes and identifies novel regulatory relationships.

Redox regulation of yeast Hsp70 modulates protein quality control while directly triggering an Hsf1-dependent cytoprotective response

This study shows that redox regulation of yeast Hsp70 affects protein quality control and activates Hsf1-dependent stress responses through cysteine modifications.

Clinical phenotypes in acute and chronic infarction explained through human ventricular electromechanical modelling and simulations

This paper uses human ventricular electromechanical modelling to explain clinical phenotypes in acute and chronic myocardial infarction, showing that ionic remodelling impacts ECG changes and ejection fraction.

The grape MYB24 mediates the coordination of light-induced terpene and flavonol accumulation in response to berry anthocyanin sunscreen depletion

The paper identifies MYB24 as a transcription factor coordinating light-induced terpene and flavonol accumulation in response to anthocyanin depletion in grape berries.

Initiation of organ maturation and fruit ripening in grapevine is controlled by the CARPO-NAC transcription factor

This study identifies VviCARPO as a key NAC transcription factor regulating grapevine fruit ripening and tissue senescence by controlling chlorophyll degradation and anthocyanin accumulation.

Design and execution of a Verification, Validation, and Uncertainty Quantification plan for a numerical model of left ventricular flow after LVAD implantation

This paper presents a numerical model of the LV-LVAD system and executes a verification, validation, and uncertainty quantification plan to ensure credible predictions of left ventricular flow.

Major orchestration of shikimate, early phenylpropanoid and stilbenoid pathways by Subgroup 2 R2R3-MYBs in grapevine

This study identifies Subgroup 2 R2R3-MYBs as key regulators of the stilbenoid pathway in grapevine by integrating DAP-Seq and co-expression networks.