Author

K. Gehring

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

G. Kozlov· 4 shared E. A. Fon· 2 shared J. Jiang· 2 shared R. Fakih· 2 shared V. Sauve· 2 shared A. Noronha· 1 shared A. Rohaim· 1 shared A. Saran· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersBiochemistry

G. Kozlov

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Enhanced binding of guanylated poly(A) RNA by the LaM domain of LARP1

G. Kozlov, J. Jiang, T. Rutherford, A. Noronha, C. Wilds, K. Gehring

This study investigates LARP1's preference for singly guanylated poly(A) RNA sequences and shows cyclic di-nucleotides bind with sub-micromolar affinity.

bioRxiv · May 8, 2024Biochemistry

Structural insights into regulation of TRPM7 divalent cation uptake by the small GTPase ARL15

L. Mahbub, G. Kozlov, P. Zong, S. Tetteh, T. Nethramangalath, C. Knorn, J. Jiang, A. Shahsavan, E. Lee, L. Yue, L. Runnels, K. Gehring

This study identifies ARL15 as a GTPase that binds CNNM2 and inhibits TRPM7-mediated divalent cation uptake, revealing molecular interactions and competitive regulation with PRL2.

bioRxiv · Jan 19, 2023Biochemistry

Selective localization of Mfn2 near PINK1 enable its preferential ubiquitination by Parkin on mitochondria

M. Vranas, Y. Lu, S. Rasool, N. Croteau, J. D. Krett, V. Sauve, K. Gehring, E. A. Fon, T. M. Durcan, J.-F. Trempe

The paper identifies Mfn2 as a preferred Parkin substrate due to its proximity to PINK1, which facilitates Parkin activation and ubiquitination on mitochondria.

bioRxiv · Aug 25, 2021Biochemistry

Structural basis for feedforward control in the PINK1/parkin pathway

V. Sauve, G. Sung, E. MacDougall, G. Kozlov, A. Saran, R. Fakih, E. A. Fon, K. Gehring

The paper elucidates how phospho-ubiquitin binds to parkin's RING domains to activate the PINK1/parkin pathway through a feedforward mechanism.

bioRxiv · Aug 16, 2021Biochemistry

Crystal structure of a bacterial CNNM magnesium transporter

Y. S. Chen, G. Kozlov, J. Armitano, B. J. Moeller, R. Fakih, A. Rohaim, B. Roux, J. E. Burke, K. Gehring

The paper determines the crystal structure of an archaeal CNNM protein bound to Mg2+-ATP, revealing its transmembrane fold and suggesting it functions as a cation transporter.

bioRxiv · Feb 11, 2021Biophysics