Author

A. ten Brinke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

T. Rispens· 3 shared G. Elias· 2 shared A. E. Oja· 1 shared A. G. Paul· 1 shared A. Saris· 1 shared B. M. Hogema· 1 shared C. A. Ghandour· 1 shared C. E. van der Schoot· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersImmunology

T. Rispens

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Deep profiling of antigen-specific B cells from different pathogens identifies novel compartments in the IgG memory B cell and antibody-secreting cell lineages

M. Claireaux, G. Elias, G. Kerster, L. H. Kuijper, M. C. Duurland, A. G. Paul, J. A. Burger, M. Poniman, W. Olijhoek, N. de Jong, R. de Jongh, E. Wynberg, H. D. van Willigen, M. Prins, G. J. de Bree, , S. M. van Ham

The paper identifies novel stages in IgG memory B cell and antibody-secreting cell differentiation by analyzing antigen-specific B cells from different pathogens using high-dimensional flow cytometry.

bioRxiv · Dec 19, 2023 · PreprintImmunology

Single-cell analysis reveals dynamics of human B cell differentiation and identifies novel B and antibody-secreting cell intermediates

N. Verstegen, S. Pollastro, P.-P. Unger, C. Marsman, G. Elias, T. Jorritsma, M. Streutker, K. Bassler, K. Haendler, T. Rispens, J. Schultze, A. ten Brinke, M. Beyer, M. S. van Ham

The paper uses single-cell RNA sequencing to study human B cell differentiation, identifying novel intermediates and a germinal-center-like population in vitro.

bioRxiv · Oct 3, 2022Immunology

Divergent SARS-CoV-2-specific T and B cell responses in severe but not mild COVID-19

A. E. Oja, A. Saris, C. A. Ghandour, N. A. M. Kragten, B. M. Hogema, E. J. Nossent, L. M. A. Heunks, S. Cuvalay, E. Slot, F. H. Swaneveld, H. Vrielink, T. Rispens, E. van der Schoot, R. A. W. van Lier, A. Ten Brinke, P. Hombrink

The paper compares T and B cell responses in severe versus mild COVID-19 patients, finding impaired CD4+ T cell responses but strong IgG antibodies in severe cases.

bioRxiv · Jun 18, 2020 · PreprintImmunology