Author

T. Rispens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 5

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 5 Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:flow cytometry· 1

Frequent Co-Authors

A. ten Brinke· 3 shared G. Elias· 2 shared T. W. Kuijpers· 2 shared A. E. Oja· 1 shared A. G. Paul· 1 shared A. Kamp· 1 shared A. Lixenfeld· 1 shared A. P. J. Vlaar· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

A. ten Brinke

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Deep profiling of antigen-specific B cells from different pathogens identifies novel compartments in the IgG memory B cell and antibody-secreting cell lineages

M. Claireaux, G. Elias, G. Kerster, L. H. Kuijper, M. C. Duurland, A. G. Paul, J. A. Burger, M. Poniman, W. Olijhoek, N. de Jong, R. de Jongh, E. Wynberg, H. D. van Willigen, M. Prins, G. J. de Bree, , S. M. van Ham

The paper identifies novel stages in IgG memory B cell and antibody-secreting cell differentiation by analyzing antigen-specific B cells from different pathogens using high-dimensional flow cytometry.

bioRxiv · Dec 19, 2023 · PreprintImmunology

Single-cell analysis reveals dynamics of human B cell differentiation and identifies novel B and antibody-secreting cell intermediates

N. Verstegen, S. Pollastro, P.-P. Unger, C. Marsman, G. Elias, T. Jorritsma, M. Streutker, K. Bassler, K. Haendler, T. Rispens, J. Schultze, A. ten Brinke, M. Beyer, M. S. van Ham

The paper uses single-cell RNA sequencing to study human B cell differentiation, identifying novel intermediates and a germinal-center-like population in vitro.

bioRxiv · Oct 3, 2022Immunology

The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylatedIgG1 in naive but not antigen-experienced vaccinees

J. Van Coillie, T. Pongracz, J. Rahmoeller, H.-J. Chen, C. E. Geyer, L. A. van Vught, J. S. Buhre, T. Sustic, T. L. J. van Osch, M. Steenhuis, W. Hoepel, W. Wang, A. Lixenfeld, J. Nouta, S. Keijzer, , Fatebenefratelli-Sacco Infectious Diseases Physic

The paper examines afucosylated IgG1 responses after BNT162b2 vaccination, finding transient responses in naive individuals that correlate with second-dose antibody levels.

bioRxiv · Feb 14, 2022Immunology

Divergent SARS-CoV-2-specific T and B cell responses in severe but not mild COVID-19

A. E. Oja, A. Saris, C. A. Ghandour, N. A. M. Kragten, B. M. Hogema, E. J. Nossent, L. M. A. Heunks, S. Cuvalay, E. Slot, F. H. Swaneveld, H. Vrielink, T. Rispens, E. van der Schoot, R. A. W. van Lier, A. Ten Brinke, P. Hombrink

The paper compares T and B cell responses in severe versus mild COVID-19 patients, finding impaired CD4+ T cell responses but strong IgG antibodies in severe cases.

bioRxiv · Jun 18, 2020 · PreprintImmunology

Unravelling the effect of a potentiating anti-Factor H antibody on atypical hemolytic uremic syndrome associated factor H variants

G. Dekkers, M. Brouwer, J. Jeremiasse, A. Kamp, R. M. Biggs, G. van Mierlo, S. Lauder, S. Katti, T. W. Kuijpers, T. Rispens, I. Jongerius

This study investigates how a potentiating anti-FH antibody enhances the function of wild-type and aHUS-associated FH variants.

bioRxiv · Apr 8, 2020 · PreprintImmunology