Author

A. Shepley-McTaggart

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Liang· 2 shared R. N. Harty· 2 shared A. B. Reitz· 1 shared A. Whigham· 1 shared B. Freedman· 1 shared C. A. Sagum· 1 shared E. Rybakovsky· 1 shared H. Ye· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

J. Liang

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2 papers

Recent·Most cited

Compound FC-10696 Inhibits Egress and Spread of Marburg Virus

Z. Han, H. Ye, J. Liang, A. Shepley-McTaggart, J. E. Wrobel, A. B. Reitz, A. Whigham, K. N. Kavelish, M. S. Saporito, B. Freedman, O. Shtanko, R. N. Harty

The paper identifies FC-10696 as a novel compound that inhibits Marburg virus egress and spread, showing antiviral effects in cell cultures and animal models.

bioRxiv · Jan 15, 2021Microbiology

SARS-CoV-2 Envelope (E) Protein Interacts with PDZ-Domain-2 of Host Tight Junction Protein ZO1

A. Shepley-McTaggart, C. A. Sagum, I. Oliva, E. Rybakovsky, K. DiGuilio, J. Liang, M. T. Bedford, J. Cassel, M. Sudol, J. M. Mullin, R. N. Harty

This study identifies a specific interaction between SARS-CoV-2 E protein and PDZ-domain-2 of ZO1, suggesting a role in epithelial barrier disruption and disease severity.

bioRxiv · Dec 22, 2020Microbiology