Lysosomal vesiculophagy terminates STING signalling
Y. Kuchitsu, K. Mukai, Y. Takaada, A. Shinojima, S. Hamano, R. Uematsu, E. Ogawa, T. Suzuki, N. Dohmae, T. Uemura, H. Arai, S. Waguri, T. Taguchi
This study identifies lysosomal vesiculophagy as a mechanism for STING degradation, preventing sustained type I interferon response.
bioRxiv · Mar 20, 2022Cell Biology