Author

S. Waguri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:proteomics· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

E. Ogawa· 2 shared H. Arai· 2 shared K. Mukai· 2 shared M. Komatsu· 2 shared N. Dohmae· 2 shared R. Uematsu· 2 shared T. Suzuki· 2 shared T. Taguchi· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

E. Ogawa

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5 papers

Recent·Most cited

Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response

M. Komatsu, R. Ikeda, D. Noshiro, H. Morishita, S. Takada, S. Kageyama, Y. Fujioka, T. Funakoshi, S. Komatsu-Hirota, R. Arai, E. Ryzhii, M. Abe, T. Koga, M. Nakao, K. Sakimura, , N. N. Noda

This study identifies ULK1 as the kinase responsible for phosphorylating p62, which activates NRF2 in a redox-independent manner through retention of KEAP1 in p62 bodies.

bioRxiv · Dec 21, 2022Cell Biology

Lysosomal vesiculophagy terminates STING signalling

Y. Kuchitsu, K. Mukai, Y. Takaada, A. Shinojima, S. Hamano, R. Uematsu, E. Ogawa, T. Suzuki, N. Dohmae, T. Uemura, H. Arai, S. Waguri, T. Taguchi

This study identifies lysosomal vesiculophagy as a mechanism for STING degradation, preventing sustained type I interferon response.

bioRxiv · Mar 20, 2022Cell Biology

Arf GTPase-Activating proteins SMAP1 and AGFG2 regulate the size of Weibel-Palade bodies and exocytosis of von Willebrand factor

A. Watanabe, H. Hataida, N. Inoue, K. Kamon, K. Baba, K. Sasaki, R. Kimura, H. Sasaki, Y. Eura, W.-F. Ni, Y. Shibasaki, S. Waguri, K. Kokame, y. shiba

This study identifies SMAP1 and AGFG2 as ArfGAPs regulating Weibel-Palade body size and von Willebrand factor exocytosis, respectively.

bioRxiv · Mar 29, 2021Cell Biology

Homeostatic regulation of STING by Golgi-to-ER membrane traffic

K. Mukai, E. Ogawa, R. Uematsu, Y. Kuchitsu, T. Uemura, S. Waguri, T. Suzuki, N. Dohmae, H. Arai, A. K. Shum, T. Taguchi

This study identifies STING as a cargo of Golgi-to-ER transport and shows that impaired retrograde transport due to COPA syndrome mutations leads to STING activation and autoinflammation.

bioRxiv · May 20, 2020Cell Biology

Autophagy controls lipid droplet formation by fine-tuning NCoR1 levels

M. Komatsu, Y.-S. Sou, M. Koike, N. Mizushima, S. Waguri, S. Terai, A. Kuma, T. Saito, S.-s. Takahashi, T. Yabe

This study shows autophagy regulates lipid droplet formation by modulating NCoR1 levels, affecting LXR target gene expression and lipid metabolism in the liver.

bioRxiv · Aug 1, 2019 · PreprintCell Biology