R. Uematsu

Lysosomal vesiculophagy terminates STING signalling

This study identifies lysosomal vesiculophagy as a mechanism for STING degradation, preventing sustained type I interferon response.

Homeostatic regulation of STING by Golgi-to-ER membrane traffic

This study identifies STING as a cargo of Golgi-to-ER transport and shows that impaired retrograde transport due to COPA syndrome mutations leads to STING activation and autoinflammation.