Author

A. Takasu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

D. I. Stuart· 1 shared H. Fukuhara· 1 shared H. M. Dokainish· 1 shared H. Sawa· 1 shared J. T. Huiskonen· 1 shared K. Maenaka· 1 shared K. Miyamoto· 1 shared K. Tabata· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

D. I. Stuart

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Native spike flexibility revealed by BSL3 Cryo-ET of active SARS-CoV-2 virions

H. Fukuhara, H. M. Dokainish, S. Kita, K. Tabata, A. Takasu, J. T. Huiskonen, Y. Anraku, T. Nomai, T. Someya, T. Senda, D. I. Stuart, M. Sasaki, Y. Orba, Y. Suzuki, H. Sawa, K. Maenaka

This study uses cryo-ET to analyze native, active SARS-CoV-2 virions, revealing a transient open-trimer prefusion state and hidden spike flexibility with implications for vaccine design.

bioRxiv · Oct 10, 2023 · PreprintMicrobiology

Transition to the structurally vulnerable nuclear state is an integral part of mouse embryonic development

T. Masahito, R. Sakanoue, A. Takasu, N. Watanabe, Y. Shimamoto, K. Miyamoto

The paper shows that mouse embryonic nuclei become structurally and mechanically vulnerable at the 2-cell stage due to lamin B1 loss via autophagy, essential for chromatin organization and zygotic genome activation.

bioRxiv · Feb 20, 2023 · PreprintCell Biology