Author

A. Talla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 5 Organism:human· 5 Approach:statistical model· 4 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

S. V. Vasaikar· 3 shared T. R. Torgerson· 3 shared E. M. Coffey· 2 shared E. W. Newell· 2 shared H. MacMillan· 2 shared J. L. Czartoski· 2 shared J. Reading· 2 shared K. W. Cohen· 2 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

S. V. Vasaikar

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6 papers

Recent·Most cited

PALMO: a comprehensive platform for analyzing longitudinal multi-omics data

S. V. Vasaikar, A. K. Savage, Q. Gong, E. Swanson, A. Talla, C. Lord, A. Heubeck, J. Reading, L. T. Graybuck, P. Meijer, T. R. Torgerson, P. Skene, T. Bumol, X.-j. Li

PALMO analyzes longitudinal multi-omics data by decomposing variations, identifying stable/variable features, and detecting markers across timepoints, validated on a complex dataset and external benchmarks.

bioRxiv · Oct 17, 2022 · PreprintImmunology

Selective loss of CD107a TIGIT+ memory HIV-1-specific CD8+ T cells in PLWH over a decade of ART

O. Blanch-Lombarte, D. Ouchi, E. Jimenez-Moyano, J. Carabelli, M. A. Marin, R. Penya, A. Pelletier, A. Talla, A. Sharma, J. Dalmau, J. R. Santos, R.-P. A. Sekaly, B. Clotet, J. G. Prado

This study identifies a selective loss of CD107a+ TIGIT+ memory HIV-1-specific CD8+ T cells in PLWH on long-term ART, which can be reversed by TIGIT blockade.

bioRxiv · Jul 13, 2022Immunology

Persistent serum protein signatures define an inflammatory subset of long COVID

A. Talla, S. V. Vasaikar, G. Szeto, M. P. Lemos, J. L. Czartoski, H. MacMillan, Z. Moodie, K. W. Cohen, L. B. Fleming, Z. Thomson, L. Okada, L. A. Becker, E. M. Coffey, S. C. DeRosa, E. W. Newell, , T. R. Torgerson

Serum proteome profiling identifies subsets of long COVID patients with evidence of persistent inflammation and key immune signaling pathways.

bioRxiv · May 9, 2022 · PreprintImmunology

Longitudinal immune dynamics of mild COVID-19 define signatures of recovery and persistence

A. Talla, S. V. Vasaikar, M. P. Lemos, Z. Moodie, M.-P. L. Pebworth, K. E. Henderson, K. W. Cohen, J. L. Czartoski, L. Lai, M. S. Suthar, A. T. Heubeck, P. C. Genge, C. R. Roll, M. Weiss, J. Reading, , T. F. Bumol

The paper profiles longitudinal immune responses in mild COVID-19 patients to identify recovery and persistence signatures.

bioRxiv · May 26, 2021 · PreprintImmunology

Microbiome and Metabolome driven differentiation of TGF-beta producing Tregs leads to Senescence and HIV latency

K. Ghneim, A. A. Sharma, S. P. Ribeiro, S. Fourati, J. Ahlers, D. Kulpa, X. Xu, J. Brehm, A. Talla, S. Arumugam, S. Darko, B. Rodriguez, C. Shive, R. Cristescu, A. Loboda, , R.-P. Sekaly

The paper identifies cellular senescence and TGF-beta pathways in HIV-infected individuals that contribute to HIV latency and poor immune recovery, suggesting potential therapeutic targets.

bioRxiv · Dec 15, 2020 · PreprintImmunology

A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection

S. Fourati, A. Talla, M. Mahmoudian, J. G. Burkhart, R. Klen, R. Henao, Z. Aydin, K. Y. Yeung, M. E. Ahsen, R. Almugbel, S. Jahandideh, X. Liang, T. E. M. Nordling, M. Shiga, A. Stanescu, , S. K. Sieberts

The paper uses crowdsourced analysis of gene expression data to identify molecular signatures predictive of susceptibility to respiratory viruses before and after exposure.

bioRxiv · Apr 30, 2018Immunology