Author

A. Tirosh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

E. Yifrach· 2 shared E. Zalckvar· 2 shared M. Eisenstein· 2 shared M. Schuldiner· 2 shared Y. Peleg· 2 shared A. Fadel· 1 shared A. Gavish· 1 shared A. Othman· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

E. Yifrach

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Author profile →

3 papers

Recent·Most cited

Determining the targeting specificity of the selective peroxisomal targeting factor Pex9

E. Yifrach, M. Ruowitz, L. D. Cruz Zaragoza, A. Tirosh, Z. Gazi, Y. Peleg, M. Kunze, M. Eisenstein, W. Schliebs, M. Schuldiner, R. Erdmann, E. Zalckvar

The paper investigates the targeting specificity of Pex9 by analyzing PTS1 motifs and structural features, finding that hydrophobicity of the amino acid before the PTS1 tripeptide determines its binding specificity.

bioRxiv · Feb 2, 2022Cell Biology

The transcriptional hallmarks of intra-tumor heterogeneity across a thousand tumors

A. Gavish, M. Tyler, D. Simkin, D. Kovarsky, L. N. Gonzalez Castro, D. Halder, R. Chanoch-Myers, J. Laffy, M. Mints, A. R. Greenwald, A. Weider, R. Tal, A. Spitzer, T. Hara, A. Tirosh, , I. Tirosh

This study integrates single-cell RNA-seq data from 1,163 tumors across 24 types to identify 41 consensus transcriptional programs and 11 hallmarks of intra-tumor heterogeneity.

bioRxiv · Dec 19, 2021 · PreprintCancer Biology

Systematic multi-level analysis of an organelle proteome reveals new peroxisomal functions

E. Yifrach, D. Holbrook-Smith, J. Burgi, A. Othman, M. Eisenstein, C. W. T. Van Roermund, W. Visser, A. Tirosh, C. Bibi, S. Galor, U. Weil, A. Fadel, Y. Peleg, H. Waterham, R. J. Wanders, , E. Zalckvar

The paper identifies new peroxisomal functions in yeast by expanding the organellar proteome and analyzing sub-organellar localization and metabolic roles.

bioRxiv · Dec 8, 2021Cell Biology