E. Zalckvar

PEX39 facilitates the peroxisomal import of PTS2 proteins

This study identifies PEX39 as a cytosolic peroxin that facilitates PTS2-protein import by interacting with PEX7 and stabilizing its binding to cargo.

Mpf1 is a novel factor that affects the dual distribution of tail-anchored proteins between mitochondria and peroxisomes

This study identifies Mpf1 as a novel factor influencing the dual targeting of tail-anchored proteins between mitochondria and peroxisomes in yeast.

Dually targeted proteins regulate proximity between peroxisomes and partner organelles

The paper investigates dually targeted proteins in yeast and shows they act as dynamic tethers between peroxisomes and partner organelles, contributing to their proximity and communication.

Determining the targeting specificity of the selective peroxisomal targeting factor Pex9

The paper investigates the targeting specificity of Pex9 by analyzing PTS1 motifs and structural features, finding that hydrophobicity of the amino acid before the PTS1 tripeptide determines its binding specificity.

Systematic multi-level analysis of an organelle proteome reveals new peroxisomal functions

The paper identifies new peroxisomal functions in yeast by expanding the organellar proteome and analyzing sub-organellar localization and metabolic roles.

Identification of Pex34p as a component of the peroxisomal de novo biogenesis machinery in yeast

The paper identifies Pex34p as a crucial factor for de novo peroxisome biogenesis in yeast, alongside Pex25p, through genetic screening and interaction studies.

Pex14p phosphorylation modulates import of citrate synthase 2 into peroxisomes in Saccharomyces cerevisiae

This study shows that phosphorylation of Pex14p at serine 266 regulates the import of Cit2p into peroxisomes, affecting yeast metabolism under different carbon sources.

An alternative membrane topology permits lipid droplet localization of peroxisomal fatty acyl-CoA reductase 1

The paper identifies Far1 as a dual topology membrane protein capable of localizing to both peroxisomes and lipid droplets, with a C-terminal hydrophobic domain mediating lipid droplet targeting.