R. Erdmann

Fast volumetric fluorescence lifetime imaging of multicellular systems using single-objective light-sheet microscopy

This paper accelerates fluorescence lifetime imaging (FLIM) using single-objective light-sheet microscopy, achieving faster and less phototoxic imaging of live multicellular systems.

High confidence glycosomal membrane protein inventory unveils trypanosomal Peroxin PEX15

The paper identifies 28 novel glycosomal membrane proteins in trypanosomes, validates four new ones, and identifies PEX15 as a key protein essential for glycosome biogenesis and parasite survival.

A novel PEX14/PEX5 interface links peroxisomal protein import and receptor recycling

This paper identifies a novel PEX14/PEX5 interface involved in peroxisomal protein import and receptor recycling through biochemical and structural analysis.

PEX1 is essential for the glycosome biogenesis and trypanosomatid parasite survival.

This study identifies TbPEX1 as essential for glycosome biogenesis and trypanosome survival, showing its role in matrix protein import and quality control mechanisms.

Intramolecular autoinhibition of human PEX13 modulates peroxisomal import

This study characterizes the PEX13 SH3 domain's interactions and autoinhibition mechanism, revealing its role in modulating peroxisomal import.

Peroxisomal ATPase ATAD1 acts in quality control of the protein import machinery

The paper investigates the role of ATAD1 in peroxisomal quality control by interacting with PEX5 and influencing its stability.

Determining the targeting specificity of the selective peroxisomal targeting factor Pex9

The paper investigates the targeting specificity of Pex9 by analyzing PTS1 motifs and structural features, finding that hydrophobicity of the amino acid before the PTS1 tripeptide determines its binding specificity.

Identification of Pex34p as a component of the peroxisomal de novo biogenesis machinery in yeast

The paper identifies Pex34p as a crucial factor for de novo peroxisome biogenesis in yeast, alongside Pex25p, through genetic screening and interaction studies.

Diffusion and interaction dynamics of the cytosolic peroxisomal import receptor PEX5

The paper characterizes the diffusion and interaction dynamics of PEX5 in the cytosol using advanced microscopy techniques, revealing a novel interaction partner.

Competitive Microtubule Binding of PEX14 Coordinates Peroxisomal Protein Import and Motility

The paper shows PEX14 binds microtubules and competes with kinesin for binding sites, linking peroxisome motility and protein import.

Pex14p phosphorylation modulates import of citrate synthase 2 into peroxisomes in Saccharomyces cerevisiae

This study shows that phosphorylation of Pex14p at serine 266 regulates the import of Cit2p into peroxisomes, affecting yeast metabolism under different carbon sources.