ImmunologybioRxiv
NETosis proceeds by cytoskeleton and endomembrane disassembly and PAD4-mediated chromatin de-condensation and nuclear envelope rupture
C. M. Waterman, H. R. Thiam, S. L. Wong…·D. D. Wagner
This study uses live-cell imaging to characterize the step-wise cellular events of NETosis in neutrophils and identifies PAD4's role in chromatin de-condensation and nuclear envelope rupture.