Gigaxonin is required for intermediate filament transport
B. Renganathan, J. P. Zewe, Y. Cheng, M. Kittisopikul, P. Opal, K. M. Ridge, V. I. Gelfand
This study shows that gigaxonin is essential for intermediate filament transport by kinesin-1, and its loss leads to IF accumulation due to increased soluble vimentin oligomers.
bioRxiv · Aug 19, 2022Cell Biology