Author

A. X. Han

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. B. Ward· 1 shared A. Fox· 1 shared A. J. W. te Velthuis· 1 shared A. S. Lauring· 1 shared A. Schorcht· 1 shared C. A. Russell· 1 shared C. LaBranche· 1 shared C. Russell· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperImmunology

A. B. Ward

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mutual information networks reveal evolutionary relationships within the influenza A virus polymerase

S. Arcos, A. X. Han, A. J. W. te Velthuis, C. Russell, A. S. Lauring

This study uses mutual information networks to analyze coevolutionary relationships among residues in the influenza A virus polymerase, revealing functional interactions and host adaptability factors.

bioRxiv · Feb 16, 2023Evolutionary Biology

CD4 binding-site antibodies induced by a subtype B HIV-1 envelope trimer

A. Schorcht, T. L. G. M. van den Kerkhof, J. Torres, E. Schermer, C. LaBranche, I. Bontjer, M. Brinkkemper, N. Gulzar, A. X. Han, J. Burger, G. Ozorowski, J. Scott, H. Schuitemaker, D. Montefiori, M. van Gils, , R. W. Sanders

This study shows that immunization with native-like HIV-1 subtype B Env trimers can induce CD4bs-directed broadly neutralizing antibodies in rabbits.

bioRxiv · Mar 23, 2022 · PreprintImmunology

Within-host evolutionary dynamics of seasonal and pandemic human influenza A viruses in young children

A. X. Han, Z. C. Felix Garza, M. R. A. Welkers, R. M. Vigeveno, N. D. Tran, T. Q. M. Le, Q. T. Pham, D. T. Dang, T. N. A. Tran, M. T. Ha, T. H. Nguyen, Q. T. Le, T. H. Le, T. B. N. Hoang, K. Chokephaibulkit, , C. A. Russell

This study examines within-host evolutionary dynamics of seasonal and pandemic influenza A viruses in young children, finding that nonsynonymous mutations decrease over time in A/H1N1pdm09 but increase in A/H3N2 due to mutation-selection balance.

bioRxiv · Mar 20, 2021Microbiology