Author

T. H. Le

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Backstrom· 1 shared A. Fox· 1 shared A. Mirazimi· 1 shared A. X. Han· 1 shared B. May· 1 shared B. Seashore-Ludlow· 1 shared C. A. Russell· 1 shared C. O. Sepulveda· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCell Biology

A. Backstrom

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Direct extrusion of multifascicle prevascularized human skeletal muscle for volumetric muscle loss surgery

V. T. Duong, T. T. Dang, V. P. Le, T. H. Le, C. T. Nguyen, H. L. Phan, J. Seo, S. H. Back, K.-i. Koo

This paper develops a method to create multifascicle human skeletal muscle scaffolds for volumetric muscle loss repair, showing that cocultured scaffolds regenerate muscle in vivo.

bioRxiv · Sep 26, 2023Bioengineering

Subcellular mapping of the protein landscape of SARS-CoV-2 infected cells for target-centric drug repurposing

J. M. Kaimal, M. Tampere, T. H. Le, U. Axelsson, H. Xu, H. Axelsson, A. Backstrom, F. Marabita, E. Moussaud-Lamodiere, D. Njenda, C. O. Sepulveda, W. Ouyang, B. Seashore-Ludlow, C. Vernersson, A. Mirazimi, , C. Stadler

The paper uses immunofluorescence to analyze host protein changes in SARS-CoV-2 infection and identifies three drugs that reduce antiviral activity.

bioRxiv · Mar 29, 2022 · PreprintCell Biology

PRE-CLINICAL IMMUNE RESPONSE AND SAFETY EVALUATION OF THE PROTEIN SUBUNIT VACCINE NANOCOVAX FOR COVID-19

T. N. M. Tran, B. May, T. T. Ung, M. K. Nguyen, T. T. Nguyen, V. L. Dinh, T. V. Tran, H. Khong, T. T. Nguyen, H. Q. H. Hua, V. A. Nguyen, T. P. Ha, D. L. Phan, T. A. Nguyen, T. N. Bui, , M. S. Do

This study evaluates the immune response and safety of the protein subunit vaccine Nanocovax in animal models, showing high immunogenicity and no adverse effects.

bioRxiv · Jul 20, 2021 · PreprintImmunology

Within-host evolutionary dynamics of seasonal and pandemic human influenza A viruses in young children

A. X. Han, Z. C. Felix Garza, M. R. A. Welkers, R. M. Vigeveno, N. D. Tran, T. Q. M. Le, Q. T. Pham, D. T. Dang, T. N. A. Tran, M. T. Ha, T. H. Nguyen, Q. T. Le, T. H. Le, T. B. N. Hoang, K. Chokephaibulkit, , C. A. Russell

This study examines within-host evolutionary dynamics of seasonal and pandemic influenza A viruses in young children, finding that nonsynonymous mutations decrease over time in A/H1N1pdm09 but increase in A/H3N2 due to mutation-selection balance.

bioRxiv · Mar 20, 2021Microbiology