A. J. W. te Velthuis

This study uses deep mutational scanning to analyze the functional constraints and evolutionary potential of the influenza A virus PB1 protein by measuring replicative fitness across most possible amino acid substitutions.

The paper examines how RNA structures in influenza A viruses change during adaptation to humans, finding reduced free energy in template loops associated with increased replication efficiency.

This study uses mutual information networks to analyze coevolutionary relationships among residues in the influenza A virus polymerase, revealing functional interactions and host adaptability factors.

The paper shows that transient RNA structures called template loops enhance innate immune activation by influenza A virus through stalling of the RNA polymerase.

This paper develops a mini-genome assay using negative-sense RNA to study SARS-CoV-2 replication inhibitors and mutations, offering high sensitivity and ease of use in standard labs.

This study demonstrates that ANP32A is essential for both vRNA and cRNA synthesis in influenza A virus replication, challenging previous assumptions about its role.

This study shows that zinc-embedded PA66 fabrics absorb and inactivate SARS-CoV-2 and influenza A virus, with stable performance after multiple washes.

This study analyzes real-time dynamics of influenza virus RNA promoters during replication, revealing differences in initiation mechanisms between vRNA and cRNA promoters.