Author

A. Zychlinsky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Biswas· 1 shared A. Foti· 1 shared A. Herzig· 1 shared A. I. Skoultchi· 1 shared A. Lindner· 1 shared A. Prasse· 1 shared B. E. Caffrey· 1 shared B. Seeliger· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

A. Biswas

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Author profile →

4 papers

Recent·Most cited

Tyrosine halogenation converts α-defensins into potent immunomodulators

A. Foti, R. Hurwitz, K. Textoris-Taube, M. Muelleder, A. Biswas, P. Fahjen, M. Winkler, U. Abu Abed, D. Humme, S. Thee, A. Prasse, B. Seeliger, M. Ralser, A. Zychlinsky

The paper identifies that tyrosine halogenation of α-defensins by hypohalous acids converts them into immunomodulatory mediators, revealing a novel oxidative mechanism in neutrophil function.

bioRxiv · Nov 1, 2023 · PreprintImmunology

Panton-Valentine leukocidin-induced neutrophil extracellular traps lack antimicrobial activity and are readily induced in patients with recurrent PVL+-Staphylococcus aureus infections

H. Jhelum, D. Cerina, C. J. Harbort, A. Lindner, L. G. Hanitsch, R. Leistner, J.-T. Schröder, H. von Bernuth, M. S. Stegemann, M. Schürmann, A. Zychlinsky, R. Krüger, G. Marsman

This study shows that PVL-induced neutrophil extracellular traps (NETs) lack antimicrobial activity and that patients with recurrent PVL-SA infections have neutrophils more susceptible to PVL-induced NET formation.

bioRxiv · Nov 26, 2021Immunology

Histone H3 Clipping is a novel signature of Human Neutrophil Extracellular Traps

D. O. Tilley, U. Abuabed, U. Zimny Arndt, M. Schmid, S. Florian, P. R. Jungblut, V. Brinkmann, A. Herzig, A. Zychlinsky

This study identifies a histone H3 cleavage event specific to neutrophil extracellular traps (NETs) and develops an antibody to detect and quantify NETs in various samples.

bioRxiv · Mar 15, 2021Immunology

Linker Histone H1 subtypes specifically regulate neutrophil differentiation

G. Sollberger, R. Streeck, B. E. Caffrey, A. I. Skoultchi, A. Zychlinsky

The paper shows that specific linker histone H1 subtypes regulate neutrophil differentiation in human and mouse models using CRISPR/Cas9 screening.

bioRxiv · Oct 29, 2019Immunology