Author

U. Abu Abed

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

A. Biswas· 1 shared A. Foti· 1 shared A. Prasse· 1 shared A. Zychlinsky· 1 shared B. Seeliger· 1 shared D. Humme· 1 shared G. Krishnamoorthy· 1 shared J. Weiner· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. Biswas

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2 papers

Recent·Most cited

Tyrosine halogenation converts α-defensins into potent immunomodulators

A. Foti, R. Hurwitz, K. Textoris-Taube, M. Muelleder, A. Biswas, P. Fahjen, M. Winkler, U. Abu Abed, D. Humme, S. Thee, A. Prasse, B. Seeliger, M. Ralser, A. Zychlinsky

The paper identifies that tyrosine halogenation of α-defensins by hypohalous acids converts them into immunomodulatory mediators, revealing a novel oxidative mechanism in neutrophil function.

bioRxiv · Nov 1, 2023 · PreprintImmunology

Inhibition of host Lactate dehydrogenase A by a small-molecule limits Mycobacterium tuberculosis growth and potentiates bactericidal activity of isoniazid

G. Krishnamoorthy, P. Kaiser, U. Abu Abed, J. Weiner, P. Moura-Alves, V. Brinkmann, S. H. E. Kaufmann

This paper shows that inhibiting host LDHA with FX11 limits M. tuberculosis growth and enhances the effectiveness of isoniazid in a mouse model of TB.

bioRxiv · May 7, 2019 · PreprintMicrobiology