Author

I. Mahouche

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1 Assay:protein sequence· 1

Frequent Co-Authors

P. Soubeyran· 2 shared A. Brunel· 1 shared A.-A. Raymond· 1 shared B. Bessette· 1 shared C. Billottet· 1 shared C. Dantzer· 1 shared C. Dussert· 1 shared C. Lamaison· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

P. Soubeyran

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Author profile →

3 papers

Recent·Most cited

Emerging role of oncogenic β-catenin in exosome biogenesis as a driver of immune escape in hepatocellular carcinoma

C. Dantzer, J. Vache, A. Brunel, I. Mahouche, A.-A. Raymond, J.-W. Dupuy, M. Petrel, P. Bioulac-Sage, D. Perrais, N. Dugot-Senant, M. Verdier-Sage, B. Bessette, C. Billottet, V. Moreau

This study shows that oncogenic β-catenin reduces exosome release in HCC, leading to immune escape by decreasing immune cell infiltration.

bioRxiv · Oct 24, 2023Cancer Biology

Anterior Gradient-2 (AGR2) is overexpressed in colon cancer and is a potential biomarker of microsatellite instability (MSI) tumors

D. Fessart, I. Mahouche, V. Brouste, V. Velasco, I. Soubeyran, P. Soubeyran, S. Pernot, E. Chevet, S. Evrard, J. Robert, F. Delom

This study finds AGR2 protein is overexpressed in colon cancer and correlates with longer survival, and is associated with microsatellite instability (MSI) tumors.

bioRxiv · Sep 7, 2021 · PreprintCancer Biology

Stromal cells regulate malignant B-cell spatial organization, survival, and drug response in a new 3D model mimicking lymphoma tumor niche

C. Lamaison, S. Latour, N. Helaine, V. Le Morvan, C. Monvoisin, I. Mahouche, C. Dussert, E. Dessauge, C. Pangault, M. Seffals, L. Broca-Brisson, K. Alessandri, P. Soubeyran, F. Mourcin, P. Nassoy, , L. Bresson-Bepoldin

The paper develops a 3D model of B-cell lymphoma using microfluidic alginate microspheres to study stromal cell interactions and drug response.

bioRxiv · Oct 17, 2020 · PreprintCancer Biology