Abed Alkader Yassin

Effect of the Environmental Mechanical Heterogeneity on T Cell Function

This study shows that T cells respond to mechanical heterogeneity by not averaging signals, leading to lower activation than on stiff surfaces, but long-term exposure enhances memory and effector T cell proliferation.

Deciphering the role of the nanoscale clustering of activating and costimulatory antibodies on T cell activation

The paper investigates how nanoscale clustering and density of activating and costimulatory antibodies influence T cell activation, finding that global density is more critical than cluster size.