Brooke L. Loveland

This paper shows that loss of PFKFB2 in cardiac cells leads to electrophysiological instability, including prolonged repolarization and ventricular tachyarrhythmia, linking glycolytic regulation to heart function.

This study identifies a metabolic myopathy in HFpEF through multiomics analysis of skeletal muscle, revealing mitochondrial dysfunction and altered amino acid metabolism.