An autologous human iPSC-derived 3D organoid infection model for preclinical testing of antiviral T cells
Ugarit Daher, Valeria Beatriz Fernández Vallone, Morris Baumgardt, Benedikt Obermayer, Niklas Wiese, Achim K. Kirsch, Tanja Fisch, Anna Löwa, Michael Schmueck‐Henneresse, Andreas Christian Hocke, Leila Amini, Harald Stachelscheid
The paper develops a 3D lung organoid model to assess antiviral T cell efficacy in vitro, demonstrating T cell-mediated cytotoxicity against influenza virus.
bioRxiv · Sep 16, 2025 · PreprintImmunology