Author

Niklas Wiese

Berlin Institute of Health at Charité - Universitätsmedizin Berlin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Approach:genetic perturbation / CRISPR· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Leila AminiiD· 2 shared Michael Schmueck‐HenneresseiD· 2 shared Abdolreza Nazari· 1 shared Achim K. Kirsch· 1 shared Anamika Giri· 1 shared Andrea Sánchez PeñaiD· 1 shared Andreas Christian HockeiD· 1 shared Andy Roemhild· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Leila AminiORCID

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Author profile →

2 papers

Recent·Most cited

Clinical development of gene edited tacrolimus-resistant Treg (FKBP12KO-Treg) to enable simultaneous immunosuppression and support of immune regulation

Ghazaleh Zarrinrad, Lisa-Marie Burkhardt, C. Beltran-Mestres, Silvina Romero‐Suárez, Dimitrios L. Wagner, Stephan Schlickeiser, Maik Stein, Désirée J. Wendering, Iván Juky Carrera Diaz de la Cebosa, Lukas Ehlen, Frederik Hamm, Gavin Kurgan, Pawel Durek, Frederik Heinrich, Anamika Giri, , Leila Amini

This paper develops gene-edited tacrolimus-resistant Treg cells (FKBP12KO-Treg) for clinical use in transplant recipients, showing they maintain immunoregulatory function while resisting tacrolimus.

Molecular Therapy Advances · Apr 9, 2026Peer-reviewedImmunology

An autologous human iPSC-derived 3D organoid infection model for preclinical testing of antiviral T cells

Ugarit Daher, Valeria Beatriz Fernández Vallone, Morris Baumgardt, Benedikt Obermayer, Niklas Wiese, Achim K. Kirsch, Tanja Fisch, Anna Löwa, Michael Schmueck‐Henneresse, Andreas Christian Hocke, Leila Amini, Harald Stachelscheid

The paper develops a 3D lung organoid model to assess antiviral T cell efficacy in vitro, demonstrating T cell-mediated cytotoxicity against influenza virus.

bioRxiv · Sep 16, 2025 · PreprintImmunology