Valeria Beatriz Fernández Vallone

StemCNV-check: a pipeline for human pluripotent stem cell (hPSC) genomic integrity control using SNP array data and copy number variant scoring

The paper introduces StemCNV-check, a pipeline for assessing genomic integrity in human pluripotent stem cells using SNP array data and CNV scoring.

An autologous human iPSC-derived 3D organoid infection model for preclinical testing of antiviral T cells

The paper develops a 3D lung organoid model to assess antiviral T cell efficacy in vitro, demonstrating T cell-mediated cytotoxicity against influenza virus.

SteMClass: A Novel DNA Methylation-Based Classifier for iPSC In Vitro Differentiation States.

SteMClass is a DNA methylation-based classifier that accurately identifies iPSC differentiation states across protocols and datasets.

DTX4 regulates neural progenitor transitions during cortical development

This study identifies DTX4 as a regulator of neural progenitor transitions during cortical development, showing its role in maintaining radial glia identity and preventing intermediate progenitor generation.

An Lgr5-independent developmental lineage is involved in mouse intestinal regeneration

The paper identifies an Lgr5-independent developmental lineage in mouse intestinal regeneration through single-cell RNA sequencing and lineage tracing experiments.

Spatiotemporal expression of thyroid hormone transporter MCT8 and THRA mRNA in human cerebral organoids recapitulating first trimester cortex development

The paper characterizes the spatiotemporal expression of MCT8 and THRA in human cerebral organoids, showing their expression patterns align with early cortical development and response to thyroid hormone treatment.

Lgr5 Controls Extracellular Matrix Production By Stem Cells In The Developing Intestine

This study shows Lgr5 regulates extracellular matrix production in fetal intestinal stem cells, affecting their maturation and niche environment.