Author
Indian Institute of Technology Gandhinagar
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Ruthwick Meduri, Aditi Lakshmi Satish, Umashankar Singh
The paper analyzes FANTOM CAGE data to identify hierarchical TSS co-deployment patterns and shows their disruption in cancers using deep learning.
Aditi Lakshmi Satish, Praveen Kumar, Ishani Morbia, Umashankar Singh
The paper shows that cancer transcriptomes have higher distal TSS deployment and altered energy costs, with gene function determining whether TSS deployment is stochastic or adaptive.
Praveen Kumar Issac, Ishani Morbia, Aditi Lakshmi Satish…·Umashankar Singh
This paper shows that CGGBP1 from higher amniotes restricts cytosine methylation and maintains GC-rich transcription factor binding sites in repressed promoters, influencing TFBS evolution.
Ishani Morbia, Praveen Kumar Issac, Aditi Lakshmi Satish…·Umashankar Singh
This study shows CGGBP1's DNA-binding domain prevents cytosine methylation at transcription factor binding sites in promoters, regulating gene expression and evolving as a key mechanism in vertebrates.