Mechanism of an animal toxin-antidote system
Lews Caro, Aguan Daniel Wei, Christopher Alex Thomas, Galen Posch, Ahmet Uremis, Michaela C. Franzi, Sarah J. Abell, Andrew H. Laszlo, Jens H. Gundlach, Jan‐Marino Ramirez, Michael Ailion
This study identifies PMPL-1 as a cofactor required for PEEL-1 toxin-induced cell death in C. elegans and shows that the toxin-antidote system creates a cation channel.
PLoS Biology · May 27, 2025Peer-reviewedCell Biology