Author

Aihua Lin

Oslo University Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:GWAS / association mapping· 3 Assay:GWAS summary statistics· 3 Research Focus:benchmarking· 1 Research Focus:polygenic risk· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alexey A. ShadriniD· 4 shared Ole A. AndreasseniD· 4 shared Oleksandr FreiiD· 4 shared Anders Martin DaleiD· 3 shared Dennis van der MeeriD· 3 shared Guy HindleyiD· 3 shared Olav Bjerkehagen SmelandiD· 3 shared Weiqiu ChengiD· 3 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenetics

Alexey A. ShadrinORCID

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4 papers

Recent·Most cited

The Norwegian Mother, Father, and Child cohort study (MoBa) genotyping data resource: MoBaPsychGen pipeline v.1

Elizabeth C. Corfield, Alexey A. Shadrin, Oleksandr Frei, Zillur Rahman, Bayram Cevdet Akdeniz, Tahir Tekin Filiz, Aihua Lin, Isabella Badini, Laura Hegemann, Lavinia Athanasiu, Robyn E. Wootton, Chloe Austerberry, Amanda Hughes, Martin Tesli, Espen Hagen, , Alexandra Havdahl

The paper describes the MoBaPsychGen pipeline for quality controlling and imputing genotyping data from the MoBa cohort, identifying extensive family relationships across 207,569 individuals.

Nature · Aug 19, 2026Peer-reviewedGenetics

Efficient meta-analysis of multivariate genome-wide association studies with Meta-MOSTest

Aihua Lin, Alexey A. Shadrin, Dennis van der Meer, Guy Hindley, Weiqiu Cheng, Ida Elken Sønderby, Shahram Bahrami, Kevin Sean O’Connell, Zillur Rahman, Nadine Parker, Olav Bjerkehagen Smeland, Chun Chieh Fan, Dominic Holland, Anders Martin Dale, Ole A. Andreassen, Oleksandr Frei

The paper introduces Meta-MOSTest, an extension of MOSTest for meta-analysis of multivariate GWAS, showing it maintains statistical power and type I error control across multiple cohorts.

bioRxiv · Aug 18, 2022 · PreprintBioinformatics

Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy and improves prediction

Guy Hindley, Alexey A. Shadrin, Dennis van der Meer, Nadine Parker, Weiqiu Cheng, Kevin Sean O’Connell, Shahram Bahrami, Aihua Lin, Naz Karadag, Børge Holen, Thomas Doug Bjella, Chun Chieh Fan, Torill Ueland, Srdjan Djurovic, Olav Bjerkehagen Smeland, , Ole A. Andreassen

This study uses a multivariate genetic approach to analyze personality and cognitive traits, identifying pleiotropy and improving polygenic prediction.

bioRxiv · Feb 28, 2022 · PreprintGenetics

Multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.

Alexey A. Shadrin, Tobias Kaufmann, Dennis van der Meer, Clare E. Palmer, Carolina Makowski, Robert J. Loughnan, Terry L. Jernigan, Tyler M. Seibert, Donald J. Hagler, Olav Bjerkehagen Smeland, Ehsan Motazedi, Yunhan Chu, Aihua Lin, Weiqiu Cheng, Guy Hindley, , Anders Martin Dale

The paper uses a multivariate GWAS approach to identify 780 genetic loci associated with cortical morphology, showing a 10-fold increase in loci compared to univariate methods.

NeuroImage · Sep 21, 2021Peer-reviewedGenetics