Author

Aimal H. Khankhel

University of California, Santa Barbara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Eyal KarzbruniD· 2 shared Sebastian J. StreichaniD· 2 shared Alex ChialastriiD· 1 shared Aryeh WarmflashiD· 1 shared Boris I. ShraimaniD· 1 shared Eric D. SiggiaiD· 1 shared George BrittoniD· 1 shared Heitor C. Megale· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenomics

Eyal KarzbrunORCID

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2 papers

Recent·Most cited

Integrated single-cell sequencing reveals principles of epigenetic regulation of human gastrulation and germ cell development in a 3D organoid model

Alex Chialastri, Eyal Karzbrun, Aimal H. Khankhel, Monte J. Radeke, Sebastian J. Streichan, Siddharth S. Dey

The paper introduces scMAT-seq, a single-cell multiomics method, to study epigenetic regulation during human gastrulation and germ cell development in 3D organoids, revealing insights into DNA methylation and accessibility dynamics.

bioRxiv · Feb 10, 2022 · PreprintGenomics

Self-organized morphogenesis of a human neural tube in vitro by geometric constraints

Eyal Karzbrun, Aimal H. Khankhel, Heitor C. Megale, Stella M.K. Glasauer, Yofiel Wyle, George Britton, Aryeh Warmflash, Kenneth S. Kosik, Eric D. Siggia, Boris I. Shraiman, Sebastian J. Streichan

This paper describes an in vitro method to self-organize a human neural tube using geometric constraints, showing that neural and epidermal tissues are sufficient for morphogenesis.

Nature · Oct 27, 2021Peer-reviewedDevelopmental Biology