Michela Fagiolini

This study identifies reduced enteric Bdnf and altered VIPergic signaling as key mechanisms of GI dysmotility in a Mecp2-null mouse model of Rett syndrome.

This study examines how different MeCP2 mutations affect neuronal activity and network function in Rett syndrome organoids, finding mutation-specific impairments in connectivity and gene expression.

This study develops a TECPR2 knock-in mouse model and shows that AAV9-mediated gene therapy improves mechanosensory function, gait, and startle responses in neonatal mice with TECPR2 deficiency.

The paper identifies hypo- and hyperconnectivity subtypes in autism using cross-species fMRI, linking them to distinct biological mechanisms in mice and humans.

The paper shows that experience during development shapes feature-selectivity in the mouse primary visual thalamus, independent of cortical feedback and dependent on retinogeniculate refinement.

The paper maps brain connectivity in 16 autism mouse models to identify four subtypes of functional connectivity abnormalities linked to different etiologies.