GeneticsGenome ResearchPeer-reviewed
Deletion of Xist upstream sequences alters TAD interactions and leads to defects in Xist coating and expression
Sudeshna Majumdar, Lakshmi Sowjanya Bammidi, Hemant Chandru Naik…·Srimonta Gayen
The paper shows that deleting Xist upstream sequences disrupts TAD organization, affects Xist expression, and leads to dysregulation of autosomal genes.