Author

Avinchal Manhas

Indian Institute of Science Bangalore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetics· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Srimonta GayeniD· 3 shared Hemant Chandru NaikiD· 2 shared Runumi Baro· 2 shared Sudeshna MajumdariD· 2 shared Akash Kalita· 1 shared Amlan Jyoti Naskar· 1 shared Amritesh Sarkar· 1 shared Deepshikha ChandeliD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenetics

Srimonta GayenORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Deletion of Xist upstream sequences alters TAD interactions and leads to defects in Xist coating and expression

Sudeshna Majumdar, Lakshmi Sowjanya Bammidi, Hemant Chandru Naik, Avinchal Manhas, Runumi Baro, Akash Kalita, Amlan Jyoti Naskar, Sundarraj Nidharshan, GS Bariha, Dimple Notani, Srimonta Gayen

The paper shows that deleting Xist upstream sequences disrupts TAD organization, affects Xist expression, and leads to dysregulation of autosomal genes.

Genome Research · Aug 6, 2025Peer-reviewedGenetics

Lineage-specific dynamics of erasure of X-upregulation during inactive-X reactivation

Hemant Chandru Naik, Deepshikha Chandel, Sudeshna Majumdar, Maniteja Arava, Runumi Baro, Harshavardhan BV, Kishore Hari, Parichitran Ayyamperumal, Avinchal Manhas, Mohit Kumar Jolly, Srimonta Gayen

The paper investigates lineage-specific coordination of X-chromosome inactivation and active-X upregulation in female cells across different developmental contexts and identifies UTF1 as a mediator of X-upregulation erasure in some lineages.

Stem Cell Reports · Oct 31, 2024Peer-reviewedGenetics

Gestational exposure to high heat-humidity conditions impairs mouse embryonic development

Avinchal Manhas, Amritesh Sarkar, Srimonta Gayen

This study establishes a mouse model of heat-humidity stress during pregnancy and shows its cumulative teratogenic effects on embryonic development, leading to higher embryonic deaths and malformations.

bioRxiv · Apr 22, 2024 · PreprintDevelopmental Biology