PAXIP1 and STAG2 converge to maintain 3D genome architecture and facilitate promoter/enhancer contacts to enable stress hormone-dependent transcription
Isabel Mayayo‐Peralta, Sebastian Gregoricchio, Karianne G. Schuurman, Selçuk Yavuz, Anniek Zaalberg, Aleksandar Kojic, Nina Abbott, Bart Geverts, Suzanne Beerthuijzen, Joseph C. Siefert, Tesa Severson, Martijn v. Baalen, Liesbeth Hoekman, Cor Lieftink, Maarten A. F. Altelaar, , Wilbert T. Zwart
This study identifies PAXIP1 and STAG2 as co-regulators of the Glucocorticoid Receptor (GR) that maintain 3D genome architecture and enable stress hormone-dependent transcription.
Nucleic Acids Research · Apr 18, 2023Peer-reviewedGenomics