Single cell 3'UTR analysis identifies changes in alternative polyadenylation throughout neuronal differentiation and in autism
Manuel Göpferich, Nikhil Oommen George, Ana Domingo-Muelas, Alex Bizyn, Rosa Pascual, Daria Fijałkowska, Georgios Kalamakis, Ulrike Müller, Jeroen Krijgsveld, Raúl Méndez, Isabel Fariñas, Wolfgang K. Huber, Simon Anders, Ana Martín-Villalba
The paper analyzes 3'UTR changes during neuronal differentiation and in ASD, finding longer 3UTRs in ASD patients and a role for CPEB4 and APLP1 in APA regulation.
bioRxiv · Aug 12, 2020 · PreprintNeuroscience