Author

Alex Vaughan

Cold Spring Harbor Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:deconvolution· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Anthony M. ZadoriD· 2 shared Xiaoyin CheniD· 2 shared Adam Henry MarblestoneiD· 1 shared Ádám KepecsiD· 1 shared Andrew G. XueiD· 1 shared Anne Cheng· 1 shared Anubhav SinhaiD· 1 shared Asmamaw T. Wassie· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersNeuroscience

Anthony M. ZadorORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Expansion Sequencing of RNA Barcoded Neurons in the Mammalian Brain: Progress and Implications for Molecularly Annotated Connectomics

Daniel Goodwin, Alex Vaughan, Daniel Leible, Shahar Alon, Gilbert Lee Henry, Anne Cheng, Xiaoyin Chen, Ruihan Zhang, Andrew G. Xue, Asmamaw T. Wassie, Anubhav Sinha, Yosuke Bando, Atsushi Kajita, Adam Henry Marblestone, Anthony M. Zador, , Richie E. Kohman

The paper introduces ExBarSeq, a method for high-resolution multiplexing of barcodes and synaptic proteins in neurons, demonstrating its application in mouse brain tissue.

bioRxiv · Jul 31, 2022 · PreprintNeuroscience

BARcode DEmixing through Non-negative Spatial Regression (BarDensr)

Shuonan Chen, Jackson Loper, Xiaoyin Chen, Alex Vaughan, Anthony M. Zador, Liam Paninski

BarDensr demixes spatial transcriptomics data by modeling the imaging process and using convex optimization, achieving state-of-the-art signal recovery in dense or low-resolution data.

PLoS Computational Biology · Mar 8, 2021Peer-reviewedGenomics

Categorical Representations Of Decision-Variables In Orbitofrontal Cortex

Junya Hirokawa, Alex Vaughan, Ádám Kepecs

The paper identifies categorical representations of decision variables in orbitofrontal cortex using rats performing a complex task, showing neurons encode distinct decision-related features.

bioRxiv · May 9, 2017 · PreprintNeuroscience