Richie E. Kohman

This study generates functional ovarian granulosa-like cells from human iPSCs by overexpressing NR5A1 and RUNX1 or RUNX2, enabling the formation of ovary-like organoids with germ cells.

The paper introduces ExBarSeq, a method for high-resolution multiplexing of barcodes and synaptic proteins in neurons, demonstrating its application in mouse brain tissue.

This study identifies key transcription factors that drive the rapid differentiation of human induced pluripotent stem cells into oogonia-like cells using a combinatorial approach and computational tools.

ExSeq enables multiplexed RNA mapping at nanoscale resolution by expanding biological specimens for in situ sequencing.

This paper introduces a method to store digital data in DNA using enzymatic synthesis guided by light patterns, demonstrating storage of 110 bits of data.

This paper introduces a method to map hundreds of proteins in tissues by sequencing DNA-conjugated antibodies, overcoming the limitations of traditional fluorescent labeling.

The paper introduces BOLORAMIS, a RT-free method for spatially-resolved, targeted in-situ RNA detection, and demonstrates its use on human iPSCs to identify spatial localization and expression heterogeneity.