α-Aminooxyacetic acid derivatives acting as pro-drugs against Mycobacterium tuberculosis
Kristin Vill, Lasse van Geelen, Oliver Michel, Anna-Lene Kiffe-Delf, Alexander Berger, David Podlesainski, Katharina Stenzel, Filip Kovačić, Beate Lungerich, Björn Burkhardt, Taylor A. Crooks, Michael D. Howe, Lev Ostrer, Ziyi Jia, Thomas R. Ioerger, , Rainer Kalscheuer
This study identifies novel anti-TB pro-drugs based on α-aminooxyacetic acid that are effective against M. tuberculosis and show low cytotoxicity.
bioRxiv · Apr 4, 2024 · PreprintMicrobiology