Author

David Podlesainski

University of Duisburg-EssenORCID 0000-0002-1111-8042Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Markus KaiseriD· 2 shared Alexander Berger· 1 shared Ann‐Christin LindåsiD· 1 shared Anna-Lene Kiffe-DelfiD· 1 shared Anthony D. BaughniD· 1 shared Beate Lungerich· 1 shared Bettina SiebersiD· 1 shared Björn Burkhardt· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Markus KaiserORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

De novo synthesis of fatty acids in Archaea via an archaeal fatty acid synthase complex

Christian Schmerling, Xiaoxiao Zhou, Paul E. Görs, Stephan Köstlbacher, Till Kessenbrock, David Podlesainski, David Sybers, Kun Wang, Ann‐Christin Lindås, Jacky L. Snoep, Eveline Peeters, Markus Kaiser, Thijs J. G. Ettema, Sven W. Meckelmann, Christopher Bräsen, Bettina Siebers

This study shows that archaea can synthesize fatty acids using a newly identified pathway and enzyme complex, providing insights into their evolutionary lipid composition.

bioRxiv · Jul 5, 2024 · PreprintMicrobiology

α-Aminooxyacetic acid derivatives acting as pro-drugs against Mycobacterium tuberculosis

Kristin Vill, Lasse van Geelen, Oliver Michel, Anna-Lene Kiffe-Delf, Alexander Berger, David Podlesainski, Katharina Stenzel, Filip Kovačić, Beate Lungerich, Björn Burkhardt, Taylor A. Crooks, Michael D. Howe, Lev Ostrer, Ziyi Jia, Thomas R. Ioerger, , Rainer Kalscheuer

This study identifies novel anti-TB pro-drugs based on α-aminooxyacetic acid that are effective against M. tuberculosis and show low cytotoxicity.

bioRxiv · Apr 4, 2024 · PreprintMicrobiology