Author

Alexander Forrest

Albert Einstein College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Antonio Di CristofanoiD· 1 shared David Mark LoebiD· 1 shared Larry H. MatherlyiD· 1 shared Noah CoppermaniD· 1 shared Sara ZirpoliiD· 1 shared Shrey D. PateliD· 1 shared Zhanjun HouiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Antonio Di CristofanoORCID

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1 paper

Recent·Most cited

Inhibition Of One-Carbon Metabolism In Ewing Sarcoma Results In Profound And Prolonged Growth Suppression Associated With Purine Depletion

Sara Zirpoli, Noah Copperman, Shrey D. Patel, Alexander Forrest, Zhanjun Hou, Larry H. Matherly, David Mark Loeb, Antonio Di Cristofano

This study shows that inhibiting one-carbon metabolism in Ewing sarcoma cells leads to growth suppression through purine depletion, identifying a potential therapeutic target.

bioRxiv · Apr 13, 2025 · PreprintCancer Biology