Transcription factor network analysis identifies REST/NRSF as an intrinsic regulator of CNS regeneration
Yuyan Cheng, Yuqin Yin, Alice Zhang, Alexander M. Bernstein, Riki Kawaguchi, Kun Gao, Kyra Potter, Hui-ya Gilbert, Yan Ao, Jing Ou, Catherine J. Fricano-Kugler, Jeffrey Louis Goldberg, Zhigang He, Clifford J. Woolf, Michael V. Sofroniew, , Daniel H. Geschwind
The paper identifies REST/NRSF as a suppressor of CNS axon regeneration using systems biology approaches and validates its role through genetic manipulations.
Nature Communications · Jul 29, 2022Peer-reviewedNeuroscience