Author

Jing Ou

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Approach:benchmark study· 1

Frequent Co-Authors

Daniel H. GeschwindiD· 3 shared Riki KawaguchiiD· 2 shared Yuyan ChengiD· 2 shared Alexander M. Bernstein· 1 shared Alice ZhangiD· 1 shared Andrew G. Elkins· 1 shared Anna YiniD· 1 shared Bogdan PaşaniuciD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersNeuroscience

Daniel H. GeschwindORCID

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3 papers

Recent·Most cited

Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cellgenomics

Jessica E. Rexach, Yuyan Cheng, Lawrence Chen, Damon Polioudakis, Li‐Chun Lin, Vivianne Mitri, Andrew G. Elkins, Anna Yin, Daniela Calini, Riki Kawaguchi, Jing Ou, Jerry I. Huang, Christopher Williams, John L. Robinson, Stephanie E. Gaus, , Daniel H. Geschwind

The paper uses single-cell genomics to identify shared and disease-specific cell states and gene regulatory networks in three dementias, revealing distinct neuroimmune mechanisms and potential therapeutic targets.

bioRxiv · Sep 29, 2023 · PreprintNeuroscience

Transcription factor network analysis identifies REST/NRSF as an intrinsic regulator of CNS regeneration

Yuyan Cheng, Yuqin Yin, Alice Zhang, Alexander M. Bernstein, Riki Kawaguchi, Kun Gao, Kyra Potter, Hui-ya Gilbert, Yan Ao, Jing Ou, Catherine J. Fricano-Kugler, Jeffrey Louis Goldberg, Zhigang He, Clifford J. Woolf, Michael V. Sofroniew, , Daniel H. Geschwind

The paper identifies REST/NRSF as a suppressor of CNS axon regeneration using systems biology approaches and validates its role through genetic manipulations.

Nature Communications · Jul 29, 2022Peer-reviewedNeuroscience

Broad transcriptomic dysregulation across the cerebral cortex in ASD

Jillian R. Haney, Brie Wamsley, George T Chen, Sepideh Parhami, Prashant S. Emani, Nathan Chang, Gil D. Hoftman, Diego de Alba, Gaurav Prashant Kale, Gokul Ramaswami, Christopher Hartl, Ting Jin, Daifeng Wang, Jing Ou, Ye Emily Wu, , Daniel H. Geschwind

The paper identifies widespread transcriptomic dysregulation across multiple cortical regions in ASD, showing regional variation and genetic enrichment in synaptic and protein folding genes.

bioRxiv · Dec 17, 2020 · PreprintNeuroscience