BiochemistryJournal of the American Chemical SocietyPeer-reviewed
A Two-Step Synthesis of Covalent Genetically-Encoded Libraries of Peptide-Derived Macrocycles (cGELs) enables use of electrophiles with diverse reactivity
James C. Walker, Arunika I. Ekanayake, Nichole J. Pedowitz…·Ratmir Derda
This paper develops a two-step synthesis method for covalent genetically-encoded libraries of peptide-derived macrocycles (cGELs) that enables the use of electrophiles with diverse reactivity by controlling reaction conditions.
DOI 10.1021/jacs.6c12299