Lela Vuković

A Two-Step Synthesis of Covalent Genetically-Encoded Libraries of Peptide-Derived Macrocycles (cGELs) enables use of electrophiles with diverse reactivity

This paper develops a two-step synthesis method for covalent genetically-encoded libraries of peptide-derived macrocycles (cGELs) that enables the use of electrophiles with diverse reactivity by controlling reaction conditions.

Structural insights into PFAS-β-lactoglobulin binding mechanism mediating PFAS toxicity

This study reveals how β-lactoglobulin binds PFAS compounds through structural analysis and molecular dynamics, showing hydrophobic and electrostatic interactions that stabilize the binding.

BinderSpace: A Package for Sequence Space Analyses for Datasets of Affinity-Selected Oligonucleotides and Peptide-Based Molecules

BinderSpace is a Python package that analyzes sequence datasets of affinity-selected molecules to identify high-affinity binders through motif analysis, clustering, and visualization.

Ultralarge Modulation of Single Wall Carbon Nanotube Fluorescence Mediated by Neuromodulators Adsorbed on Arrays of Oligonucleotide Rings

This paper develops an ultrasensitive nanosensor for dopamine and norepinephrine using ssDNA-SWNT conjugates and elucidates the photophysical mechanisms behind its fluorescence modulation.